N-(3-Octyl-4-oxo-1,3-thiazolidin-2-ylidene)benzamide
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چکیده
منابع مشابه
N-(3-Octyl-4-oxo-1,3-thiazolidin-2-ylidene)benzamide
In the title compound, C(14)H(16)N(2)O(2)S, the thia-zolidine ring is planar [maximum atomic deviation = 0.0080 (14) Å] and twisted slightly with respect to the phenyl ring, making a dihedral angle of 4.46 (14)°. The butyl group displays an extended conformation, with a torsion angle of 169.4 (4)°. In the crystal structure, weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules, forming ...
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The title compound, C(26)H(24)FNO(3), is a critical inter-mediate of a selective and competitive inhibitor of the enzyme 3-hy-droxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase. Inter-molecular N-H⋯O hydrogen bonding generates a chain along [give direction] that is the dominant inter-action in the crystal packing. Inter-molecular C-H⋯O inter-actions are also observed.
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A series of novel N-[2-(substitutedphenyl)-5-methyl-4-oxo-1,3-thiazolidin-3-yl]benzamides (4a-g) were synthesized and structurally confirmed by elemental analysis, IR, H NMR and MS spectral data. Further, the antiviral screening of N-[2-(substitutedphenyl)-5-methyl-4-oxo-1,3-thiazolidin-3-yl]benzamides (4a-g) against a broad panel of DNA and RNA viral strains indicated that N-[2-(4-chlorophenyl...
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1,3-Thiazolidin-4-one analogues are important because of its versatile biological actions. In the present study, benzohydrazide (1) on condensation with different aromatic aldehydes (2a-g) in presence of catalytic amount of concentrated hydrochloric acid in absolute ethanol yield N'-[(E)(substitutedphenyl)methylidene]benzohydrazide (3a-g), which on cyclisation with 2sulfanylpropanoic acid in dr...
متن کامل(4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide
The title compound, C(21)H(21)N(3)O(7)S, contains an oxazolidinone ring and a sulfonamide group, both characteristic for biologically and pharrmaceutically active compounds. Both stereogenic centres reveal an S absolute configuration. The two oxazolidinone rings are in an envelope conformation with the methyl-ene carbon flap atoms deviating by 0.428 (1) and 0.364 (2) Å from the best least-squar...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2010
ISSN: 1600-5368
DOI: 10.1107/s1600536810047884